OUR INGREDIENTS

Juvecol®

TYPE OF PRODUCT

Proprietary salmon cartilage extract

ACTIVE COMPONENTS

Proteoglycans

SOURCE

100% Wild-caught Salmon (Oncorhynchus keta)

PART USED

Nasal cartilage

ORIGIN

Japan

SUPPLIER

Maypro

TYPE OF PRODUCT
ACTIVE COMPONENTS
SOURCE
PART USED
ORIGIN
SUPPLIER
Proprietary salmon cartilage extract Proteoglycans 100% Wild-caught Salmon (Oncorhynchus keta) Nasal cartilage Japan Maypro
Juvecol®

Proteoglycans are a component of connective tissues such as bone, cartilage, and skin. Made from proteoglycans extracted from the cartilage of salmon, Juvecol is a NEXTY Award winning ingredient clinically documented to support skin health.

The effect of salmon cartilage proteoglycans (sPG) on skin health was evaluated in a randomized, placebo-controlled, double-blind human clinical trial. Supplementation for 2 weeks improved multiple indices of skin condition, including elasticity, moisture, and appearance (reducing blotchiness, wrinkles, and pore size).

UNLOCKING NATURE

Proteoglycans (PGs) can be found in connective tissues such as skin, bone, and cartilage, where they form a complex with collagen, hyaluronic acid, and other glycoproteins. Human articulation consists of cartilage cells, cartilage matrix, tendons, and ligaments around the articulation and muscles. These components undergo various changes as our bodies age.

BIOASSAY AND CLINICAL STUDIES

To examine the effect of ingestion of PGs on skin condition, a randomized, double-blind, controlled study was performed. The results showed that viscoelasticity and recovery after deformation as the skin elasticity increased significantly in the sPG group compared to the placebo group. Skin looseness significantly decreased in the sPG group. Moreover, the number of wrinkles, conspicuous or darkened facial pores, and blotches significantly decreased in the sPG group.

Methods: Recruited subjects (n=156) were men and women, ages 21-62 years. From this population, we selected 19 subjects based on the exclusion criteria of the guidelines for evaluation of cosmetic functions of Japanese Cosmetic Science Society. Subjects were randomly divided into an sPG group (n=10; mean age, 39.1 years) and a placebo group (n=9; mean age, 39.6 years). The characteristics of the sPG used in this study were assessed by HPLC and electrophoresis analysis.
MECHANISM OF ACTION

Skin: sPG induces the production of collagen and hyaluronan and enhances the proliferation of keratinocytes (skin cells).*

Skin and joints: sPG also stimulates immunity in the gut and lymphatic system, which helps maintain a balance of excitatory and inhibitory cytokines.*

A UNIQUE PARTNERSHIP

When Maypro was founded in 1977 by the Japanese entrepreneur Steve Yamada, it was a small company with a big vision — to improve human health and happiness by importing the best-quality nutraceutical ingredients and fine chemicals to the US market from Asia.

Maypro established itself as the pioneer of novel specialty ingredients., and today it has grown into one of the largest speciality suppliers of nutraceutical ingredients and fine chemicals.

AWARDS

In 2007, Steve Yamada was recognized as the Finalist at the 15th Annual Convention of Seiwa Jukku – a global entrepreneurship organization consisting of 8,200 members in Japan, the United States, China, Brazil and Taiwan. That same year, Steve was honored with the prestigious Lifetime Achievement Award from the Nutrition Business Journal. And in 2013, Steve was presented with the highly prestigious Inamori Management Award by Kazuo Inamori, Japan’s legendary business leader who founded the electronics giant Kyocera and the leading telecom provider KDDI.

Maypro CEO Steve Yamada has been honored with two prestigious awards:

2007 Nutrition Business Journal Lifetime Achievement Award, issued by Nutrition Business Journal, an executive newsletters for the natural, nutrition and complementary & alternative health industries 2013 Inamori Management Award, issued by Seiwaijyuku, an international business training organization.

The New Hope NEXTY award

The New Hope NEXTY award at Natural Products Expo West & Engredea highlights the most progressive, innovative, inspiring and trustworthy products in the natural products industry. In 2017, Maypro was honored with the New Hope NEXTY Award for Best New Ingredient: Juvecol®

In addition, Juvecol® is also Dairy Free, Gluten Free and Non-GMO certified.