Stable peptide identical natural carcinine
10% of carcinine (2HCl) , β alanyl-histamine dihydrochloride
|Stable peptide identical natural carcinine||10% of carcinine (2HCl) , β alanyl-histamine dihydrochloride||Monaco||IONTEC|
The world’s second-smallest country — Monaco is home to IONTEC, the expert in functional food patented ingredients.
IONTEC is a Monegasque company that supplies unique and patented ingredients to the industry, in the fields of Nutrition, Health and Beauty. By selecting sustainable and innovative raw materials, they provide patented and science-based ingredients to ensure consumer safety and high-performance efficacy.
Advanced Glycation End products (AGEs) are formed by non-enzymatic reactions between carbonyl groups of sugars and free amino group of proteins, lipids or nucleic acids. Age, epigenetic factors, oxidative stress, UV, smoke, diabetes and diet are important causes of AGEs accumulation in the body. AGEs accumulation can lead to complications such as premature skin aging.
The proteins with a slow turn-over such as collagen and elastin are the most affected by the glycation process. Carcinine, a natural dipeptide especially found in brain, muscles and skin, is proven to be effective to fight against AGEs accumulation and associated oxidative damages.
Carnosine is a peptide well-known for its anti-glycation properties. Nevertheless, its efficacy may be limited by its poor resistance to degradation enzymes like carnosinase. The decarboxylation of the carnosine in carcinine modifies the resistance of the peptide but not its efficacy. Carcinine is resistant to enzyme degradation for superior bioavailability and efficacy.
To give you the best against glycation, IONTEC has developed a stable natural carnosine analog.
Carcinine has all the health benefits of carnosine with a superior bioavailability thanks to its resistance to carnosinase.
An exploratory clinical study has been conducted with 38 overweight patients in order to evaluate the benefits of GLYCOLESS® supplementation against the effects of glycation. The study was conducted with 200mg/day vs placebo for 90 days.
The parameters measured were general metabolism and skin aspect.
Reduction of glycated hemoglobin (HbA1C)
Reduction of abdominal circumference
Improvement of skin aging signs